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KMID : 0376219810180020289
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Chonnam Medical Journal
1981 Volume.18 No. 2 p.289 ~ p.297
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Experimental Study on the ´Repair Process of the Joint Cartilage Defect
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Abstract
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The theory as to the repair process for the defect of articular cartilage is still controversial; A defect may heal with the proliferation of the chondrocyte or it may be replaced with the granulation tissue from subchondral bones. In most instances the subchondral bone drilling is common clinical management, however, is always being followed by the repair with fibrous or fibrocartilagenous tissue, never with cartilage. The defects of the articular cartilage were produced in the rabbit knee joints, in the one side of which the drilling into the subchondral bone was done by fine K-wire and in the other side the defect was left without drilling.
The results were as follows.
In both groups(with drilling and with no drilling) the chondral defects were repaired by immature fibroblasts until fourth week. The repair process was observed to be most active at the superficial layer of the defect which were replaced by immature fibrotic tissue at the second week in both groups. In the group with no drilling, chondroblasts began to appear in the part of the defect at the seventh week. And at the ninth week, the defect was completely replaced by hyaline cartilage. But in the group with subchondral bone drilling the fibrotic tissues was observed at the ninth week and the death of chondrocyte in the cartilage adjacent to the defect was evident until the fourth week.
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KEYWORD
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